PRODUCT DETAILS

About Alzumab 25mg Injection

ITOLIZUMAB belongs to the class of 'immunomodulators', primarily used to treat psoriasis. Psoriasis is a skin disorder in which skin cells multiply and form bumpy (uneven) red patches covered with white scales. ITOLIZUMAB may also be used to treat autoimmune conditions like rheumatoid arthritis and multiple sclerosis. ITOLIZUMAB is currently being used and trialled to treat cytokine storm (excessive immune response) in COVID-19 (Corona Virus Disease-19) patients. 

Uses of Alzumab 25mg Injection

Psoriasis

Medicinal Benefits of Alzumab 25mg Injection

ITOLIZUMAB treats inflammation in patients with psoriasis and rheumatoid arthritis. It contains 'Itolizumab,' which is a humanized recombinant IgG1 (Immunoglobulin G1) monoclonal antibody. It works by reducing the synthesis of cytokine, a substance released by the body that initiates an inflammatory response. Lately, ITOLIZUMAB is also being used in COVID-19 infection to reduce breathing complications, the severity of inflammation, and damage in the lungs. It is being used to decrease the cytokine storm, an excessive immune response that occurs in the lungs of a COVID-19 infected person. 

Directions for Use

A healthcare professional will administer the infusion. Do not self-administer.

Side Effects of Alzumab 25mg Injection

• Pain and swelling at the injection site
• Upper respiratory tract infection
• Fever
• Itching
• Dizziness
• Diarrhoea 

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Inform your doctor if you have any liver, heart or kidney diseases, bone marrow suppression, low blood cell count, weak immune system (HIV), neutropenia (low levels of neutrophils), lymphopenia (low levels of lymphocytes), tuberculosis, hepatitis B, C, and active infections before starting ITOLIZUMAB. Avoid close contact with people who have infections like chickenpox, measles, tuberculosis, and flu that can be easily spread. Thoroughly wash your hands to prevent the spread of infection. Do not take live vaccines while being treated with ITOLIZUMAB to prevent any serious consequences. ITOLIZUMAB may cause dizziness, so drive only if you are alert and focused. Avoid consuming alcohol along with ITOLIZUMAB as it could lead to increased dizziness. ITOLIZUMAB is not recommended in children and adolescents younger than 18 years of age as safety and efficacy is not established. Store ITOLIZUMAB at temperatures of 2°C to 8°C. Do not freeze the vial.

Drug Interactions

Drug-Drug Interaction:

ITOLIZUMAB may interact with live vaccines. Let your doctor know if you use any prescription and over the counter medicines, including vitamins and herbal supplements, before starting ITOLIZUMAB

Drug-Disease Interaction:

ITOLIZUMAB should be used with caution in cases of liver, heart or kidney diseases, bone marrow suppression, low blood cell count, weak immune system (HIV), neutropenia, lymphopenia, tuberculosis, hepatitis B, C, and active infections.

Safety Advice

ALCOHOL

You are recommended to avoid alcohol consumption while taking ITOLIZUMAB. Alcohol intake, along with ITOLIZUMAB, may cause increased dizziness.

PREGNANCY

• ITOLIZUMAB is not recommended during pregnancy since it may have harmful effects on the developing baby. Your doctor will prescribe ITOLIZUMAB only if the benefit outweighs the risk.

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BREAST FEEDING

It is not known if ITOLIZUMAB passes into the breastmilk when used by breastfeeding mother. Your doctor will prescribe ITOLIZUMAB only if the benefit outweighs the risk.

DRIVING

ITOLIZUMAB may make you feel dizzy. Do not drive or operate machinery if you experience dizziness.

LIVER

Please consult your doctor since ITOLIZUMAB should be used with caution in patients with liver impairment/liver disease. Dose adjustment may be needed in patients with liver impairment. However, ITOLIZUMAB is not recommended in patients with active liver diseases.

KIDNEY

Please consult your doctor since ITOLIZUMAB should be used with caution in patients with kidney impairment/kidney disease. Dose adjustment may be required.